Personalized surgery for children with obstructive sleep apnea and small tonsils
Official title: A Personalized Surgical Approach for the Treatment of Children with Obstructive Sleep Apnea and Small Tonsils
Funded at Oregon Health & Science University · NIH-10931337 · Data updated 2026-11-12
This study is looking at a new way to help kids with obstructive sleep apnea, especially those with small tonsils, by comparing a personalized surgery to the usual tonsil removal surgery, to see which one works better for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $324,317 |
| NIH project number | 5R61HL162771-02 |
| Project ID | NIH-10931337 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 2 to 18 years who have been diagnosed with obstructive sleep apnea and have clinically small tonsils.
✕Less likely to help
Patients who do not have obstructive sleep apnea or those with enlarged tonsils may not benefit from this research.
What this research studies
This research investigates a new surgical approach for treating obstructive sleep apnea (OSA) in children, particularly those with small tonsils. It aims to determine if a personalized surgical method, guided by drug-induced sleep endoscopy (DISE), is more effective than the standard treatment of adenotonsillectomy (AT). By observing the specific patterns of airway obstruction during sleep, the study seeks to tailor surgical interventions to individual needs, potentially improving outcomes for affected children. The research will involve a randomized controlled trial comparing these two surgical strategies in children aged 2 to 18 years.
Why it matters
Potential benefit: If successful, this research could lead to more effective surgical treatments for children with obstructive sleep apnea, improving their quality of life and reducing associated health risks.
How similar studies have gone: While the use of drug-induced sleep endoscopy has shown promise in adults, this personalized approach in children is novel and has not been extensively tested.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Lam, Derek J — Oregon Health & Science University
- Study coordinator: Lam, Derek J
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.