Personalized support for managing uncertain lung nodules

Individually-tailored clinical decision support for management of indeterminate pulmonary nodules

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10539247

This study is working on a helpful tool for doctors to better manage uncertain lung nodules found during low-dose CT scans, so patients can get personalized care based on their health history and other important information.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded)
Locations1 site (LOS ANGELES, UNITED STATES)
Trial IDNIH-10539247 on ClinicalTrials.gov

What this research studies

This research focuses on developing a clinical decision support tool to help manage indeterminate pulmonary nodules (IPNs) detected through low-dose computed tomography (LDCT) lung screenings. It aims to improve patient outcomes by creating predictive models that consider a patient's evolving medical history and clinical data. By integrating various biomarkers and continuous monitoring, the tool will provide tailored management strategies for patients with IPNs, addressing the uncertainty surrounding their potential to become cancerous.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been found to have indeterminate pulmonary nodules during lung screening procedures.

Not a fit: Patients without indeterminate pulmonary nodules or those with confirmed benign nodules may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and personalized management of lung nodules, potentially improving early detection and treatment of lung cancer.

How similar studies have performed: Previous research has shown promise in developing predictive models for lung nodules, but this approach aims to enhance those models with real-time patient data, making it a novel endeavor.

Where this research is happening

LOS ANGELES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancers, neoplasm/cancer, Disease, Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.