Personalized strategies for managing HIV
Dynamic Strategies for the clinical management of HIV disease
This project builds new data tools to discover better treatment plans for people living with HIV using real-world medical records.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard University D/b/a Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11091446 on NIH RePORTER |
What this research studies
You will benefit from researchers analyzing large collections of clinic records and long-term follow-up from people with HIV to learn which treatment orders and timing lead to better health. The team will create new statistical methods to handle messy observational data and test those methods on existing clinic and registry datasets from the U.S. and Africa. They will prove the methods work and share the tools with doctors and researchers so results can inform care. This work uses existing patient data and does not directly change anyone's current treatment.
Who could benefit from this research
Good fit: Ideal candidates are people living with HIV whose care and treatment history are included in participating clinics or HIV registries with longitudinal follow-up.
Not a fit: People without medical records in the study databases, those not treated at participating sites, or newly diagnosed individuals without follow-up data are unlikely to see direct benefit.
Why it matters
Potential benefit: Could help clinicians choose the right HIV drugs and the best times to switch or adjust therapy so patients stay healthier longer.
How similar studies have performed: Related observational and data-driven studies have informed HIV care before, but applying advanced dynamic-treatment methods to complex HIV datasets is a relatively new approach.
Where this research is happening
Boston, United States
- Harvard University D/b/a Harvard School of Public Health — Boston, United States (Active)
Researchers
- Principal investigator: Hernan, Miguel — Harvard University D/b/a Harvard School of Public Health
- Study coordinator: Hernan, Miguel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.