NIH-funded research R01 grant

Personalized reports for environmental and biological test results

Official title: From the Cell to the Street: Personalized Report-Back in Large Cohort Studies with Multi-Level Measurements

Funded at Silent Spring Institute · NIH-11385316 · Data updated 2026-11-12

This project builds easy-to-understand, smartphone-friendly reports that explain environmental exposures and biological test results for people who joined pregnancy cohorts.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSilent Spring Institute
NIH-funded
Lab location1 site (Newton, United States)
Project startMay 20, 2024
Project endFebruary 29, 2028
Funding year2026
Award (this year)$387,653
NIH project number5R01ES036234-03
Project IDNIH-11385316 on NIH RePORTER

Who could benefit from this research

Could help

Primary participants are pregnant people enrolled in the Chemicals in Our Bodies (CIOB) or Illinois Kids Development Study (IKIDS) cohorts who provided biospecimens and exposure data.

Less likely to help

People who did not provide biomonitoring or exposure data or who are not enrolled in the listed cohorts are unlikely to receive personalized reports from this project.

What this research studies

If you joined one of these pregnancy cohorts, the team will gather your environmental, chemical, and cellular measurements and turn them into a personalized report you can view on a phone. They will adapt and expand the Digital Exposure Report-Back Interface (DERBI) so it can handle hundreds of measures from neighborhood data, biomonitoring, and cellular indicators. The reports will be piloted and refined using feedback from participants in the Chemicals in Our Bodies (CIOB) and Illinois Kids Development Study (IKIDS) cohorts. The project aims to find clear, participant-centered and ethically sound ways to share complex exposome information back to large groups of participants.

Why it matters

Potential benefit: If successful, people who gave samples could get clearer, actionable explanations of their exposures and biological results to help inform personal or public-health decisions.

How similar studies have gone: The project builds on the already-used DERBI tool, which has returned chemical exposure results in other cohorts, but applying report-back to large, multi-level exposome data across pregnancy cohorts is a newer effort.

Where this research is happening

  • Silent Spring Institute
    Newton, United States
    Active

Researchers

  • Principal investigator: Brody, Julia Green — Silent Spring Institute
  • Study coordinator: Brody, Julia Green

Related research

Other NIH-funded projects on the same topics.

  • PFAS in drinking water and blood pressure in adults and kids

    This project looks at how chemical PFAS in drinking water may be linked to high blood pressure in both adults and children.

    NIH research Silent Spring Institute · Newton, United States · NIH-11453182

  • Identifying early signs of breast cancer using advanced biological techniques

    This study is looking for early signs that might show if someone is at risk for breast cancer by checking how certain chemicals affect the body, using lab tests with rodents to learn more about these effects, and it hopes to help improve ways to prevent cancer in the future.

    NIH research Silent Spring Institute · Newton, United States · NIH-11076837

  • Understanding the effects of PFAS in drinking water on children's immune health

    This study is looking at how certain chemicals in drinking water, called PFAS, might affect the immune health of children in communities that have been exposed to these substances, especially from firefighting foams, and it aims to create helpful resources to inform families about the health risks and options available

    NIH research Silent Spring Institute · Newton, United States · NIH-10436901

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.