NIH-funded research R01 grant

Personalized quality-of-life tools for people with mental health and chronic conditions

Official title: Personalized Quality of Life Measurement

Funded at Mclean Hospital · NIH-11397309 · Data updated 2026-11-12

Building personalized quality-of-life measures to better show how mental health and conditions like diabetes affect people's daily lives.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMclean Hospital
NIH-funded
Lab location1 site (Belmont, United States)
Project startAugust 1, 2024
Project endApril 30, 2028
Funding year2026
Award (this year)$549,472
NIH project number5R01MH137075-03
Project IDNIH-11397309 on NIH RePORTER

Who could benefit from this research

Could help

Adults with mental health conditions and/or chronic physical illnesses such as diabetes who can complete questionnaires and share their health information may be ideal candidates.

Less likely to help

People who cannot complete surveys, are not receiving care at participating sites, or have conditions outside the study's focus may not directly benefit.

What this research studies

This project is creating new, personalized quality-of-life measures that reflect how mental health symptoms and physical conditions like diabetes affect everyday functioning. Researchers will work with patients and clinicians to collect patient-reported outcomes, clinical data, and feedback to design measures that capture what matters most to people. They plan to compare these new measures across different conditions so treatments can be compared on a common scale. Pilot testing will likely happen in clinical settings to refine the questions and make the tools practical for routine care.

Why it matters

Potential benefit: If successful, these tools could help clinicians choose treatments that improve overall functioning and help policymakers and payers allocate resources based on real patient impact.

How similar studies have gone: Existing quality-of-life tools exist for specific conditions, but combining personalized, mental-health-sensitive measures that work across conditions is relatively new and still being tested.

Where this research is happening

  • Mclean Hospital
    Belmont, United States
    Active

Researchers

  • Principal investigator: De Nadai, Alessandro Stevens — Mclean Hospital
  • Study coordinator: De Nadai, Alessandro Stevens

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.