Personalized postpartum care after preeclampsia
Multi-Omics for Maternal Health after Preeclampsia
['FUNDING_U01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11141862
Researchers will combine biological tests, health records, and environmental information to find patterns that could help women who had preeclampsia stay healthier after pregnancy.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11141862 on ClinicalTrials.gov |
What this research studies
If you had preeclampsia, this project will collect blood and other biological samples, medical records, and information about your environment and symptoms after delivery. Scientists will run multiple kinds of lab tests (like genetics, proteins, and metabolites) and link those results to clinical and exposure data. They will use computer modeling and machine learning to identify different subtypes of preeclampsia and see which ones raise the risk of future heart problems. The aim is to create more personalized follow-up care to prevent postpartum complications, especially cardiovascular disease.
Who could benefit from this research
Good fit: Women who recently experienced preeclampsia or other hypertensive disorders during pregnancy, especially those within the first year after delivery and from diverse racial and ethnic backgrounds.
Not a fit: People who never had preeclampsia or whose pregnancy was many years ago may not get direct benefit from this specific project.
Why it matters
Potential benefit: Could enable more tailored postpartum monitoring and earlier prevention of heart disease for women who had preeclampsia.
How similar studies have performed: Previous studies have linked preeclampsia to later heart disease, but applying multi-omics and machine learning to define subtypes and guide care is a newer approach still being tested.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAURENT, LOUISE CHANG — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: LAURENT, LOUISE CHANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.