Personalized online adaptive proton therapy for cancer treatment
Intelligent and Personalized Online Adaptive Proton Therapy
This study is looking at how to make proton therapy for cancer patients even better by using smart technology that adjusts treatment plans on the spot, helping to ensure that the radiation hits the right spot even if your body changes during treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11159734 on NIH RePORTER |
What this research studies
This research focuses on improving proton therapy for cancer patients by using advanced artificial intelligence to adapt treatment plans in real-time. It addresses the challenges posed by anatomical changes during treatment, such as tumor shrinkage and patient weight loss, which can affect the accuracy of radiation delivery. By developing an online adaptive proton therapy system, the goal is to minimize treatment interruptions and enhance the effectiveness of radiation therapy, particularly for patients with tumors near critical organs. The approach aims to streamline the workflow, making it less resource-intensive and more responsive to changes in patient anatomy.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients undergoing proton therapy, especially those with tumors located near critical organs.
Not a fit: Patients who are not receiving proton therapy or those with tumors that do not require adaptive treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer radiation treatments for cancer patients, reducing side effects and improving quality of life.
How similar studies have performed: Other research has shown promise in using adaptive techniques in radiation therapy, but this specific approach utilizing real-time AI adaptation is relatively novel.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Yang, Xiaofeng — Emory University
- Study coordinator: Yang, Xiaofeng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.