Personalized nutrition for adults in New England
Clinical Center for NIH's Nutrition for Precision Health: The All Of Us New England Research Collaborative
This project tests whether controlled diets, meal challenges, and biological samples can show how adults—including people with adult-onset (type 2) diabetes—differ in metabolic and gut microbiome responses.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Boston NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11239083 on NIH RePORTER |
What this research studies
You would report your usual diet and take part in a mixed-meal challenge to measure immediate metabolic responses. You may follow three different 14-day, calorie-matched diets either at home or during a short residential stay while researchers collect blood, stool, and other physiological measurements. Those data will be combined with All of Us health records to build prediction tools for personalized nutrition. The effort is led by Tufts University and Massachusetts General Hospital and aims to enroll diverse participants across New England.
Who could benefit from this research
Good fit: Ideal candidates are adults (21+) in New England, including those with adult-onset/type 2 diabetes, who can follow prescribed diets, provide blood and stool samples, and attend short in-person visits or residential stays.
Not a fit: People under 21, pregnant individuals, or those unable to follow diet changes or provide biospecimens or attend visits are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, this work could lead to personalized diet recommendations that improve blood sugar control, metabolism, and gut health for people with adult-onset diabetes.
How similar studies have performed: Previous precision-nutrition and mixed-meal challenge studies have shown promise for predicting individual metabolic responses, but large, diverse clinical programs like this are still relatively new.
Where this research is happening
Boston, United States
- Tufts University Boston — Boston, United States (Active)
Researchers
- Principal investigator: Das, Sai Krupa — Tufts University Boston
- Study coordinator: Das, Sai Krupa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.