Personalized medicine for emergency room patients
Clinical Expansion of Precision Medicine in the Emergency Department
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-11196226
This project uses quick genetic testing and computer-guided prescribing to help emergency room doctors pick safer, more effective medicines for patients who come to the ED.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-11196226 on ClinicalTrials.gov |
What this research studies
If you come to the emergency room, clinicians may do a genetic test that shows how your body processes certain medications and then receive computerized guidance to choose drugs and dosages that fit you. The team will expand decision support tools to include interactions between your genes and other medications you take. Testing and decision support will be used during the ED visit and shared for follow-up care, while researchers track return ED visits, hospital admissions, and costs. The study will also examine whether this approach is practical in a busy emergency setting.
Who could benefit from this research
Good fit: Ideal candidates are ED patients who are starting new medications or who have had medication-related problems where genetic differences in drug metabolism might matter.
Not a fit: Patients not receiving medications affected by the tested genes, those needing immediate life‑saving interventions where prescribing cannot be changed, or people who already have relevant genetic results may not benefit.
Why it matters
Potential benefit: If successful, this could reduce medication side effects and treatment failures, lower return ED visits, and help doctors choose better medicines faster.
How similar studies have performed: Pharmacogenetic testing has shown benefits in outpatient and some inpatient settings, but applying it directly in emergency departments is a newer approach with limited prior evidence.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DUARTE, JULIO DAVID — UNIVERSITY OF FLORIDA
- Study coordinator: DUARTE, JULIO DAVID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.