Personalized kidney and bladder cancer screening for people with chronic kidney disease

Tailored Screening for Urinary System Cancers in Patients with Chronic Kidney Disease

['FUNDING_R01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-11083712

This project looks at ways to tailor screening to find kidney and bladder cancers earlier in people who have chronic kidney disease.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCOLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11083712 on ClinicalTrials.gov

What this research studies

If you have chronic kidney disease (CKD), your risk of kidney and bladder cancers may be higher, yet there are no clear cancer screening rules for people like you. A team at Columbia will combine patient data, clinical expertise in nephrology and urology, and decision-science methods to identify who is at highest risk and which screening approaches might work best. They will compare possible screening options and weigh benefits and harms across different ages and levels of kidney function. The goal is to produce clearer, personalized screening guidance that clinicians can use when caring for patients with CKD.

Who could benefit from this research

Good fit: Adults with chronic kidney disease—especially middle-aged and older adults or those with moderate reductions in kidney function—would be the main candidates for these tailored screening approaches.

Not a fit: People without CKD, or those with very limited life expectancy or severe other illnesses where screening risks outweigh benefits, may not receive benefit from these screening strategies.

Why it matters

Potential benefit: If successful, this work could lead to screening recommendations that help detect urinary cancers earlier in people with CKD and guide doctors on who should be screened.

How similar studies have performed: Previous studies have shown higher rates of kidney and bladder cancer in CKD patients, but testing of tailored screening strategies is limited and formal guidelines are lacking.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.