Personalized insulin decision support for adults with brittle type 1 diabetes
Improving intensive insulin therapy through the personalization of data-driven decision support system to patients’ goals and preferences and its adaptation to long term health needs
This project creates a personalized, data-driven tool to give insulin advice tailored to adults with brittle type 1 diabetes and their changing goals.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-11296505 on NIH RePORTER |
What this research studies
From my point of view, the team is building a digital decision-support system that uses my glucose data and personal preferences to suggest insulin actions that fit my life. They will adapt the system to people who use multiple daily injections or who cannot access automated insulin delivery. The researchers will build on two decades of algorithm work and then validate the system with adult patients to make sure its advice stays aligned with long-term needs. The goal is advice that changes as my routines, risks, and goals change over time.
Who could benefit from this research
Good fit: Adults (21+) with brittle type 1 diabetes who struggle with hypoglycemia, hyperglycemia, or wide glucose swings and who use multiple daily injections or lack access to automated insulin delivery.
Not a fit: Children, people without type 1 diabetes, or those already well controlled on an automated insulin delivery system may not see benefit from this tool.
Why it matters
Potential benefit: If successful, this could help adults with brittle type 1 diabetes reduce dangerous lows and highs and meet long-term glucose targets more consistently.
How similar studies have performed: Automated insulin delivery and some decision-support tools have improved control for many patients, but tailoring algorithmic advice to individual goals and long-term needs is a newer approach.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Breton, Marc D — University of Virginia
- Study coordinator: Breton, Marc D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.