Personalized immunosuppression for kidney transplant patients
Official title: Individualized Immunosuppression for Kidney Transplant Recipients
Funded at New York University School of Medicine · NIH-11015002 · Data updated 2026-11-12
This study is working on a special tool to help find the best medication plan for people who have received a kidney transplant, aiming to reduce side effects and improve their overall health.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 22, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $154,907 |
| NIH project number | 5K01DK132490-03 |
| Project ID | NIH-11015002 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have received a kidney transplant and require ongoing immunosuppression therapy.
✕Less likely to help
Patients who have not undergone kidney transplantation or those who are not on immunosuppression therapy may not benefit from this research.
What this research studies
This research aims to develop a personalized tool to determine the best immunosuppression regimen for kidney transplant recipients. By analyzing individual risk factors, the goal is to minimize the side effects associated with immunosuppression, such as infections and cardiovascular diseases, which significantly impact patient health. The approach involves a combination of clinical data and patient-centered evidence to tailor treatment plans specifically for each recipient. This individualized strategy seeks to improve long-term health outcomes for kidney transplant patients.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective immunosuppression strategies, enhancing the longevity and quality of life for kidney transplant recipients.
How similar studies have gone: Previous research has indicated the importance of individualized treatment approaches in transplant medicine, suggesting that this personalized strategy could yield significant improvements in patient outcomes.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Bae, Sunjae — New York University School of Medicine
- Study coordinator: Bae, Sunjae
Related research
Other NIH-funded projects on the same topics.
-
Optimizing Immunosuppression and EBV-Seronegative Kidney Allocation to Reduce PTLD Risk
This grant explores how adjusting immunosuppression and kidney donor matching by EBV status could lower the risk of EBV-related cancers in kidney transplant patients.
-
Finding the best ways to prevent cancer in kidney transplant patients from Epstein-Barr Virus.
This study is looking at how different ways of lowering the immune system's activity can help kidney transplant patients who receive organs from donors with a virus called Epstein-Barr, and it hopes to find better ways to prevent complications after the transplant.
-
Microbial clues to diagnose and predict infections in kidney transplant patients
A patient-focused project will look for microbial biomarkers in stool, blood, and urine to help doctors predict and diagnose infections in people who have had a kidney transplant.
-
Immunological mechanisms behind treatment-resistant kidney transplant rejection
This grant explores why certain kidney transplant rejections don’t respond to standard treatments and what immune cells in the graft are driving that resistance.
-
Complement-Bound Exosomes and Kidney Transplant Immunity
This project studies how kidney transplant injury and rejection happen after surgery and whether blocking certain immune pathways during organ preservation could improve transplant outcomes.
-
Blood vessel signals predicting heart problems after kidney transplant
This project studies blood markers and tissue patterns after kidney transplants to identify which patients are at highest risk of cardiovascular problems.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.