Personalized imaging markers for Alzheimer's disease
Official title: Shape-based personalized AT(N) imaging markers of Alzheimer's disease
Funded at University of Southern California · NIH-10667903 · Data updated 2026-11-12
This study is looking at new ways to take pictures of the brain to better understand Alzheimer's disease, helping to spot it earlier and tailor treatments for different people based on their unique brain shapes and patterns.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | June 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $2,169,981 |
| NIH project number | 1RF1AG077578-01A1 |
| Project ID | NIH-10667903 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those at risk, particularly from diverse backgrounds.
✕Less likely to help
Patients with other forms of dementia unrelated to Alzheimer's disease may not benefit from this research.
What this research studies
This research focuses on developing advanced imaging markers for Alzheimer's disease by utilizing shape analysis techniques. It aims to create personalized assessments of the disease's pathology, specifically targeting the variability in brain structure and the atypical patterns of Alzheimer's. By analyzing biological markers such as amyloid plaques and tau tangles, the project seeks to improve early detection and understanding of the disease, particularly in diverse populations. The approach is designed to address the limitations of existing imaging methods that do not account for individual differences in brain anatomy.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and personalized diagnostic tools for Alzheimer's disease, improving patient outcomes.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for Alzheimer's, but this approach aims to innovate further by focusing on personalized assessments.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Shi, Yonggang — University of Southern California
- Study coordinator: Shi, Yonggang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.