Personalized digital support for opioid recovery
Official title: Real World Adoption of an OUD Digital Health Therapeutic
Funded at Biomedical Development Corporation · NIH-11301042 · Data updated 2026-11-12
A smartphone program called KIOS that gives people with opioid use disorder personalized, real-time support for cravings, mood, pain, and staying in treatment.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biomedical Development Corporation NIH-funded |
| Lab location | 1 site (San Antonio, UNITED STATES) |
| Project start | August 1, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $778,031 |
| NIH project number | 4R44DA059017-02 |
| Project ID | NIH-11301042 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with opioid use disorder, especially those receiving or eligible for medication for OUD who own a smartphone and want digital support, are the likely candidates.
✕Less likely to help
People without reliable smartphone access, those who prefer only in-person therapy, or individuals with unstable severe psychiatric conditions may not benefit from this digital approach.
What this research studies
You would use an app that regularly checks how you are feeling and tracks symptoms like cravings, mood, and pain. The software maps your symptom patterns and uses those patterns to decide when and what kind of help to send you, such as coping strategies or motivational messages. The project tests KIOS in real-world clinical settings alongside standard medication treatment for OUD to see how people adopt and use it. The team is working toward FDA clearance so the app could become an approved treatment tool.
Why it matters
Potential benefit: If successful, the app could help people stay in treatment, reduce relapse, and better manage cravings and mood with timely, personalized support.
How similar studies have gone: Some digital tools combined with medication for OUD have shown promise, but fully personalized, real-time adaptive digital therapeutics like KIOS are relatively new and still being tested.
Where this research is happening
-
Biomedical Development Corporation
San Antonio, United States Active
Researchers
- Principal investigator: Siegel, Gregg — Biomedical Development Corporation
- Study coordinator: Siegel, Gregg
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.