Personalized digital support for opioid recovery

Real World Adoption of an OUD Digital Health Therapeutic

['FUNDING_SBIR_2'] · BIOMEDICAL DEVELOPMENT CORPORATION · NIH-11301042

A smartphone program called KIOS that gives people with opioid use disorder personalized, real-time support for cravings, mood, pain, and staying in treatment.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorBIOMEDICAL DEVELOPMENT CORPORATION (nih funded)
Locations1 site (San Antonio, UNITED STATES)
Trial IDNIH-11301042 on ClinicalTrials.gov

What this research studies

You would use an app that regularly checks how you are feeling and tracks symptoms like cravings, mood, and pain. The software maps your symptom patterns and uses those patterns to decide when and what kind of help to send you, such as coping strategies or motivational messages. The project tests KIOS in real-world clinical settings alongside standard medication treatment for OUD to see how people adopt and use it. The team is working toward FDA clearance so the app could become an approved treatment tool.

Who could benefit from this research

Good fit: Adults with opioid use disorder, especially those receiving or eligible for medication for OUD who own a smartphone and want digital support, are the likely candidates.

Not a fit: People without reliable smartphone access, those who prefer only in-person therapy, or individuals with unstable severe psychiatric conditions may not benefit from this digital approach.

Why it matters

Potential benefit: If successful, the app could help people stay in treatment, reduce relapse, and better manage cravings and mood with timely, personalized support.

How similar studies have performed: Some digital tools combined with medication for OUD have shown promise, but fully personalized, real-time adaptive digital therapeutics like KIOS are relatively new and still being tested.

Where this research is happening

San Antonio, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.