Personalized diet plans to reduce blood sugar spikes in type 2 diabetes
Personalized Dietary Management in Type 2 Diabetes
['FUNDING_R01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11400543
This trial tests whether personalized meal guidance to lower post-meal blood sugar helps adults with early type 2 diabetes more than a standard Mediterranean-style diet or usual care.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11400543 on ClinicalTrials.gov |
What this research studies
If you join, you'll be randomly assigned to one of three groups: a standardized lifestyle program using a Mediterranean-style ADA diet, that same program plus personalized guidance to minimize post-meal blood sugar, or usual care. The team will follow 255 people for six months and use continuous glucose monitoring to measure blood sugar swings (mean amplitude of glycemic excursion, MAGE) and track HbA1c, beta-cell function, and medication changes. Personalized guidance is based on each person's individual meal responses to help pick foods and combinations that limit spikes. The study compares average outcomes between groups to see which approach keeps blood sugars lower with fewer medication escalations.
Who could benefit from this research
Good fit: Adults with early-stage type 2 diabetes who are willing to follow dietary guidance and attend study visits are the ideal candidates.
Not a fit: People with advanced diabetes requiring complex insulin regimens, type 1 diabetes, or major uncontrolled illnesses may not benefit from this dietary-focused approach.
Why it matters
Potential benefit: If successful, this could lower post-meal blood sugar swings and reduce the need for extra diabetes medications.
How similar studies have performed: Prior trials using one-size-fits-all diets have had mixed or mostly negative results, while personalized meal-response approaches are newer and show promise but remain under study.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POPP, COLLIN JEFFREY — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: POPP, COLLIN JEFFREY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus