Personalized deep brain stimulation for Parkinson's disease

Simplified, Scalable 24-hour adaptive deep brain stimulation for Parkinson’s disease

NIH-funded research University of California, San Francisco · NIH-11040802

This study is testing a new kind of brain stimulation that can change throughout the day to better help people with Parkinson's disease manage their symptoms and improve their daily lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11040802 on NIH RePORTER

What this research studies

This research focuses on developing a new type of deep brain stimulation (DBS) that adapts to the changing needs of Parkinson's disease patients throughout the day. By using advanced technology to monitor neural signals, the stimulation can be adjusted in real-time to improve motor symptoms and enhance quality of life. The approach aims to overcome the limitations of traditional DBS, which does not respond to the dynamic clinical states of patients. The research builds on previous studies that have shown promising results in improving patient outcomes with adaptive DBS.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with advanced Parkinson's disease who are experiencing motor symptoms that are not adequately controlled by current therapies.

Not a fit: Patients with early-stage Parkinson's disease or those who do not respond to deep brain stimulation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with Parkinson's disease, significantly improving their daily functioning and quality of life.

How similar studies have performed: Previous studies have shown that adaptive DBS can improve motor symptoms and quality of life, indicating a promising direction for this research.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions advanced disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.