Personalized deep brain stimulation for epilepsy treatment
Personalized Deep Brain Stimulation for Epilepsy
This study is looking to help people with epilepsy who don't find relief from regular medications by using a special treatment that targets specific areas of their brain, making it more personalized and effective just for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11054774 on NIH RePORTER |
What this research studies
This research focuses on improving treatment for epilepsy, particularly for patients who do not respond to standard medications. It aims to personalize deep brain stimulation by targeting specific areas of the brain based on individual seizure networks. Using advanced techniques like stereotactic intracranial EEG, the study will map brain connectivity and optimize stimulation parameters to enhance treatment effectiveness. Patients will be monitored closely to assess how their brain networks respond to stimulation, allowing for tailored interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with epilepsy who have not found relief from conventional drug treatments and are considering deep brain stimulation.
Not a fit: Patients with epilepsy who respond well to existing medications or those who do not qualify for deep brain stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective epilepsy treatments that significantly reduce or eliminate seizures for patients with drug-resistant epilepsy.
How similar studies have performed: Previous research has shown promise in using personalized approaches to neuromodulation, but this specific method of targeting and stimulation is relatively novel.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Gregg, Nicholas M — Mayo Clinic Rochester
- Study coordinator: Gregg, Nicholas M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.