Personalized care to reduce stress and prevent early births

Personalized care for prenatal stress reduction and preterm birth prevention

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10856908

This study is testing a special program designed to help pregnant women, especially Black women at higher risk for preterm birth, manage stress better to help prevent early deliveries, and it includes tools, support, and financial help for those who need it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10856908 on NIH RePORTER

What this research studies

This research focuses on developing a personalized program called UNC PTBCARE+ aimed at reducing stress during pregnancy to prevent preterm births. It will involve a randomized controlled trial with 1,509 pregnant patients, particularly targeting Black women who are at a higher risk for preterm birth. The program includes a stress reduction toolkit, psychosocial support, and financial assistance for those who need it. The effectiveness of these interventions will be measured through surveys and biological markers to assess stress levels and the incidence of preterm births.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women, especially those who identify as Black and are experiencing high levels of stress.

Not a fit: Patients who are not pregnant or those who do not experience significant stress may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly lower the rates of preterm births among high-risk pregnant patients by effectively managing stress.

How similar studies have performed: Previous research has shown promising results in using personalized interventions to reduce stress and improve pregnancy outcomes, indicating that this approach has potential for success.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.