Personalized care to help Black men who have sex with men start and stick with HIV prevention (PrEP)
A randomized clinical trial of client-centered care coordination to improve pre-exposure prophylaxis use for Black men who have sex with men
This project offers personalized care coordination to help Black men who have sex with men decide to start, access, and stay on HIV prevention medication (PrEP).
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11366160 on NIH RePORTER |
What this research studies
You would be asked to join a randomized program in Washington, DC or New York City where some participants get client-centered care coordination (C4) that helps with PrEP decision-making, access, and day-to-day adherence while others receive usual services. The study will compare different levels or 'doses' of C4 to find how much support works best for keeping people on PrEP. Researchers will track PrEP use, adherence measures, and whether the C4 approach is acceptable and feasible in community clinics. This work builds on a prior pilot (HPTN 073) that showed promise and will be conducted in real-world clinic settings through 2028.
Who could benefit from this research
Good fit: Ideal participants are HIV-negative Black men who have sex with men who are at risk for HIV and can attend clinic visits in Washington, DC or New York City.
Not a fit: People who are HIV-positive, not eligible for PrEP, not in the target demographic, or unable to access the study sites are unlikely to benefit from joining.
Why it matters
Potential benefit: If successful, this could help more Black men at risk for HIV start and maintain PrEP use, reducing their risk of infection.
How similar studies have performed: An earlier pilot trial (HPTN 073) showed promising results for the C4 model, but larger randomized trials are needed to confirm its effectiveness.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Whitfield, Darren Lovell — University of Maryland Baltimore
- Study coordinator: Whitfield, Darren Lovell
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.