Personalized care for gout and related health issues
Official title: Personalized Comorbidity-Integrated Gout Care
Funded at Massachusetts General Hospital · NIH-10867510 · Data updated 2026-11-12
This study is looking to make gout treatment better by creating personalized care plans that take into account your other health issues, so you can feel your best while managing your gout.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $176,040 |
| NIH project number | 5K23AR081425-02 |
| Project ID | NIH-10867510 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with gout who also have other chronic health conditions, such as kidney disease or heart disease.
✕Less likely to help
Patients who do not have gout or significant comorbidities may not benefit from this research.
What this research studies
This research focuses on improving the care of patients with gout by integrating personalized treatment plans that consider their other health conditions. The approach involves understanding how gout interacts with various comorbidities, such as chronic kidney disease and cardiovascular issues, to tailor therapies that enhance patient outcomes. Patients will be engaged in their care through a patient-centered model, ensuring that their preferences and health goals are prioritized. The research will utilize advanced methodologies to analyze patient data and develop effective treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with gout, improving their overall health and quality of life.
How similar studies have gone: Previous research has shown promising results in personalized treatment approaches for chronic conditions, suggesting that this integrated care model could be effective for gout as well.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Yokose, Chio — Massachusetts General Hospital
- Study coordinator: Yokose, Chio
Related research
Other NIH-funded projects on the same topics.
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Treat-to-Target Urate in Gout: A New Approach for Better Pain and Health
A large clinical trial tests whether aiming for a specific uric acid level in gout patients improves symptoms and health outcomes compared with avoiding symptoms.
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Translational Genomics in Gout: Linking GWAS Signals to Mechanisms
Aims to understand why some people with high uric acid develop gout by connecting genetic clues to the biology of joint inflammation.
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Genetic clues to gout flares through cell gene activity in blood and joint fluid
Researchers will study how genes turn on or off in immune cells from blood and joint fluid during gout flares to understand why flares happen.
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Uric acid skin sensor to guide gout treatment and diet
A skin patch that measures uric acid in sweat is being tested to help people with gout manage their diet and medications better.
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Wearable skin patch that tracks uric acid and metabolites for people with gout
A wearable skin patch will measure uric acid and other metabolites around meals to help people with gout make better diet and medication choices.
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Gout and Kidney Disease: How gout changes as kidney disease gets worse and after kidney transplant
This project follows people with gout as their kidney disease progresses toward dialysis or transplant, using national kidney data to understand how often gout flares happen and how care needs change.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.