Personalized brain training guided by your body's nervous system for mild memory problems
Develop an ANS-based Personalized Cognitive Training for Mild Cognitive Impairment
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-11177053
A personalized brain-training program that uses signals from your autonomic nervous system to help people with mild cognitive impairment get more benefit from processing-speed exercises.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11177053 on ClinicalTrials.gov |
What this research studies
You would do computerized speed-of-processing exercises while researchers measure signals from your autonomic nervous system (for example heart-rate patterns) to see how your body responds during learning. The team will build a "personalization engine" (called pSOPT) that combines those nervous-system signals with learning performance to tailor the training to each person. First they will refine the program and test feasibility, then they will run a preliminary trial to see if the personalized approach improves learning and brain health in people with MCI. Advanced time-series data methods will be used to create the personalization rules and guide who gets which kinds of training.
Who could benefit from this research
Good fit: Ideal participants are older adults diagnosed with mild cognitive impairment who can use a computer and are medically stable enough to participate in training and brief physiological recordings.
Not a fit: People with advanced dementia, severe sensory or motor impairments that prevent using the training, or unstable medical conditions are unlikely to benefit from this program.
Why it matters
Potential benefit: If successful, this could make computerized cognitive training work better for people with mild cognitive impairment and help preserve thinking and daily function longer.
How similar studies have performed: Previous speed-of-processing training has helped some older adults but results vary, and using autonomic nervous system signals to personalize training is a relatively new and promising approach.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIN, FENG VANKEE — STANFORD UNIVERSITY
- Study coordinator: LIN, FENG VANKEE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's disease pathology