Personalized blood pressure management for stroke recovery

Precision blood pressure management after endovascular stroke therapy based on real-time autoregulation measurements

NIH-funded research Yale University · NIH-10909211

This study is looking at how to better manage blood pressure for people who have had an ischemic stroke by using real-time brain measurements to find the best blood pressure levels for each person, helping to prevent further brain injuries.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10909211 on NIH RePORTER

What this research studies

This research focuses on developing a personalized approach to managing blood pressure in patients who have suffered an ischemic stroke. By utilizing real-time measurements of cerebral autoregulation, the study aims to identify optimal blood pressure ranges tailored to individual patients. This method seeks to prevent secondary brain injuries that can occur due to improper blood flow after a stroke. The research employs advanced techniques such as near-infrared spectroscopy to monitor brain blood flow and adjust treatment accordingly.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients who have experienced an ischemic stroke due to large-vessel occlusion.

Not a fit: Patients who have not suffered an ischemic stroke or those with other types of brain injuries may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved recovery outcomes for stroke patients by minimizing secondary brain injuries.

How similar studies have performed: Preliminary data suggests that similar approaches using autoregulation-guided blood pressure management have shown promise, indicating potential for success in this research.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.