Personalized antibiotic dosing for critically ill patients
Antibiotic Model-Informed Precision Dosing in Critical Illness
This study is looking at how to give the right amount of antibiotics to critically ill patients based on their unique needs, so they get the best treatment without unnecessary side effects.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10883749 on NIH RePORTER |
What this research studies
This research investigates how to tailor antibiotic dosing for critically ill patients based on individual responses and disease factors. It aims to move away from the standard one-size-fits-all approach, which can lead to ineffective treatment or toxicity. By utilizing real-time drug concentration data and population pharmacokinetic models, the study seeks to identify which patients would benefit most from personalized dosing strategies. The goal is to improve patient outcomes by ensuring effective antibiotic exposure while minimizing risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically ill patients in intensive care units who require antibiotic treatment.
Not a fit: Patients who are not critically ill or do not require antibiotics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer antibiotic treatments for critically ill patients.
How similar studies have performed: Other research has shown promising results with personalized dosing approaches in similar contexts, indicating potential for success in this area.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Tang Girdwood, Sonya C — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Tang Girdwood, Sonya C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.