Personalized Anesthesia Care for Asian Americans
Precision medicine for Asian Americans requiring anesthesia
This work explores how genetic differences in Asian Americans might affect their body's response to anesthesia during surgery, aiming to make anesthesia safer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11088798 on NIH RePORTER |
What this research studies
When you have surgery, your body naturally produces toxic substances called reactive aldehydes, which can harm organs. For many Asian Americans, a common genetic difference makes it harder for their bodies to clear these toxic substances, potentially leading to organ damage after surgery. This project looks closely at these genetic differences to understand how they impact organ injury during surgical procedures. By understanding these unique responses, we hope to develop new ways to protect patients and improve surgical outcomes.
Who could benefit from this research
Good fit: This research is particularly relevant for Asian Americans, especially those of East Asian descent, who may undergo surgery requiring anesthesia.
Not a fit: Patients without the specific genetic variants being studied, or those not undergoing surgery with general anesthesia, may not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could lead to personalized anesthesia approaches that better protect Asian American patients from organ damage during and after surgery.
How similar studies have performed: This foundational work aims to unlock novel treatment strategies by understanding specific genetic differences, suggesting a novel approach rather than building on established similar successes.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Gross, Eric Richard — Stanford University
- Study coordinator: Gross, Eric Richard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.