Penn program to understand and improve primary glomerular kidney diseases
CureGN-Penn PCC
Following children and adults with primary glomerular kidney diseases over time while collecting health information and biological samples to learn what affects outcomes and treatment responses.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11167654 on NIH RePORTER |
What this research studies
This project follows people like me—children and adults diagnosed with minimal change disease, focal segmental glomerulosclerosis, IgA nephropathy, or membranous nephropathy—over many years. Doctors and researchers collect clinical data, patient-reported outcomes, and biospecimens so they can study how the diseases start, change, and respond to care. The effort is part of a large national consortium with many clinical sites and a central data coordinating team. Samples and detailed records are stored to support many different research and translational projects.
Who could benefit from this research
Good fit: People of any age diagnosed with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), IgA nephropathy (IgAN), or membranous nephropathy (MN) are the intended participants.
Not a fit: Individuals without these primary glomerular diseases or those seeking an immediate experimental therapy are unlikely to get direct treatment benefits from this observational program.
Why it matters
Potential benefit: If successful, the work could help doctors predict disease course better and tailor treatments to improve outcomes for people with these kidney diseases.
How similar studies have performed: Long‑term observational cohorts have previously yielded important insights in kidney disease care, and CureGN is larger and more detailed than most earlier efforts.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Holzman, Lawrence B. — University of Pennsylvania
- Study coordinator: Holzman, Lawrence B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.