Penn Cure Glomerulonephropathy Clinical Center
CureGN-Penn PCC
Collecting health information and biological samples from adults and children with primary glomerular kidney diseases like MCD, FSGS, IgA nephropathy, and membranous nephropathy to help improve care and treatments.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11381254 on NIH RePORTER |
What this research studies
If I join this Penn arm of the CureGN network, I would become part of a long-term group of adults and children with primary glomerular kidney diseases who share clinical information and biospecimens. The team collects medical records, lab results, kidney biopsy data, patient-reported outcomes, and blood/urine/tissue samples over time. I would be seen at participating clinical centers for scheduled follow-up visits and might be invited to join additional ancillary studies that use the cohort data and samples. The study links these data to learn how the diseases progress and why patients respond differently to treatments.
Who could benefit from this research
Good fit: Adults and children diagnosed with minimal change disease, focal segmental glomerulosclerosis, IgA nephropathy, or membranous nephropathy who can attend visits at a participating center and are willing to provide samples and health information.
Not a fit: People without these primary glomerular diseases, those unable or unwilling to provide follow-up or biospecimens, or those with unrelated kidney conditions are unlikely to receive direct benefit from joining.
Why it matters
Potential benefit: This work could lead to better ways to predict disease course, identify targets for new therapies, and personalize treatment for people with these kidney diseases.
How similar studies have performed: Large observational kidney cohorts have previously helped identify clinical patterns and biomarkers, and CureGN builds on that success with a larger, deeper, multi-center dataset.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Holzman, Lawrence B. — University of Pennsylvania
- Study coordinator: Holzman, Lawrence B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.