Peer support to improve TB and HIV treatment in Uganda

Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda

['FUNDING_R01'] · YALE UNIVERSITY · NIH-11184485

Peer-led education and adherence counseling offers adults with tuberculosis, with or without HIV, extra support to stay on their TB and HIV medicines in Uganda.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-11184485 on ClinicalTrials.gov

What this research studies

If you are an adult newly diagnosed with TB at a participating clinic in Uganda, trained peers who have had TB will provide education, individualized adherence planning, and behavior-change messages to help you complete treatment. Clinics will change workflows and use a simple checklist so peers can deliver consistent TB and HIV counseling and follow-up. The project runs at 16 sites and compares outcomes between clinics using the peer-navigation approach and those using usual care. Study staff will track treatment adherence and clinical outcomes for people with and without HIV to see whether the peer approach helps more people finish therapy and stay healthy.

Who could benefit from this research

Good fit: Adults newly diagnosed with tuberculosis at one of the participating clinics in Uganda, including people living with HIV, are the intended candidates.

Not a fit: Children, people not seen at the participating clinics, or those with types of TB requiring highly specialized care (for example certain drug-resistant TB cases) may not be eligible or benefit from this program.

Why it matters

Potential benefit: If successful, this approach could help more people complete TB treatment, improve HIV care for those living with HIV, and reduce deaths from TB in the community.

How similar studies have performed: Peer-navigation and peer-led counseling have shown promise in HIV care and the project’s preliminary evaluation found the adapted peer TB counseling was feasible, acceptable, and improved TB literacy and some treatment outcomes.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.