Peer and family support to help people stay on HIV and opioid treatment in Johannesburg

An intervention integrating peer navigation and family engagement to improve ART and OST adherence in South Africa

NIH-funded research Arizona State University-Tempe Campus · NIH-11194429

The team will see if combining peer navigators with family engagement helps people who inject drugs in Johannesburg stay on HIV treatment (ART) and opioid substitution therapy (OST).

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus NIH-funded
Lab location1 site (Scottsdale, United States)
Project IDNIH-11194429 on NIH RePORTER

What this research studies

If you join this project at the Yeoville Clinic in Johannesburg, trained peer navigators will work with you and your family to support taking HIV medicines (ART) and opioid substitution therapy (OST). The researchers will assemble evidence-based family-engaged practices and give extra training to peer navigators to deliver the combined support. They will deliver the intervention through the clinic and follow participants to track treatment adherence, retention, and viral suppression over time. This pilot builds on the clinic's existing free ART-OST program and aims to see how the new approach works in a real-world, high-need community.

Who could benefit from this research

Good fit: Ideal participants are people who inject drugs living with HIV in Johannesburg who are receiving or eligible for ART and OST at the Yeoville Clinic.

Not a fit: People who do not inject drugs, who live outside the clinic's catchment area, or who are unwilling to involve family members are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, this approach could help more people who inject drugs stay on treatment, achieve viral suppression, and reduce harm from opioid use.

How similar studies have performed: Peer navigation and family-engaged support have shown promise in other HIV programs, but combining them specifically for people who inject drugs in South Africa is relatively new.

Where this research is happening

Scottsdale, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.