Pediatric Glomerular Disease Consortium (CureGN)
CUREGN 3.0 - Pediatric Nephrology Consortium - PCC
This long-term program follows children with several types of glomerular kidney disease and collects health information and samples to learn what influences outcomes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-11169924 on NIH RePORTER |
What this research studies
If your child joins, the consortium will track their health over time, record treatments and symptoms, and ask about quality of life. Clinics at many pediatric nephrology centers collect blood, urine, biopsy and medical-record data and send de-identified information to a central database. Researchers, patient advocates, and industry partners use those data and biospecimens to study causes, disease course, and treatment responses. The effort is coordinated across more than 60 sites to support future clinical trials and better care.
Who could benefit from this research
Good fit: Children and young adults diagnosed with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), IgA nephropathy (IgAN), or membranous nephropathy (MN) are the main candidates for participation.
Not a fit: People without those specific glomerular diagnoses, or those who cannot travel to a participating site or decline biospecimen collection, are unlikely to benefit directly from joining.
Why it matters
Potential benefit: If successful, this work could help predict disease course, identify causes, and guide better treatments for children with glomerular kidney diseases.
How similar studies have performed: Large observational registries like CureGN have already produced important insights into these kidney diseases, though many questions remain and further data are needed.
Where this research is happening
Columbus, United States
- Research Inst Nationwide Children's Hosp — Columbus, United States (Active)
Researchers
- Principal investigator: Smoyer, William E — Research Inst Nationwide Children's Hosp
- Study coordinator: Smoyer, William E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.