Pediatric Gastroparesis Registry 2: tracking symptoms and gastric emptying in kids and young adults
Official title: Pediatric Gastroparesis Registry 2 Study (PGpR2) supplement
Funded at Texas Tech University Health Sciences Center at El Paso · NIH-11354505 · Data updated 2026-11-12
This registry follows children, teens, and young adults (ages 8–25) with symptoms like nausea, vomiting, bloating, early fullness, or abdominal pain to document symptom patterns, gastric emptying, and quality of life over time.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Tech University Health Sciences Center at El Paso NIH-funded |
| Lab location | 1 site (El Paso, United States) |
| Project start | September 30, 2008 |
| Project end | July 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $61,800 |
| NIH project number | 3U01DK074035-16S1 |
| Project ID | NIH-11354505 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people aged 8–25 who have ongoing symptoms suggestive of gastroparesis (nausea, vomiting, early satiety, bloating, or chronic abdominal pain), whether or not prior tests showed delayed gastric emptying.
✕Less likely to help
People without gastroparesis-like symptoms, those outside the 8–25 age range, or those unwilling/unable to attend follow-up visits and complete questionnaires are unlikely to benefit from this registry.
What this research studies
You would join a multi-center registry that collects medical history, clinical measures, gastric emptying results, and patient-reported symptom and quality-of-life questionnaires over about 48 weeks. The team compares participants who have delayed gastric emptying (gastroparesis) with those who have similar symptoms but normal emptying. Data are collected at regular visits and with standardized survey tools used in pediatric gastroenterology. The goal is to understand how symptoms change, what factors link to worse outcomes, and how physiological and psychological features differ between groups.
Why it matters
Potential benefit: If successful, this work could help clinicians better match treatments to kids and young adults with gastric-emptying problems or similar symptoms and improve symptom management over time.
How similar studies have gone: Adult registries and smaller pediatric studies have described symptom patterns and gastric emptying differences, but large multi-center pediatric registries like this are relatively uncommon and aim to fill that gap.
Where this research is happening
-
Texas Tech University Health Sciences Center at El Paso
El Paso, United States Active
Researchers
- Principal investigator: Sarosiek, Irene — Texas Tech University Health Sciences Center at El Paso
- Study coordinator: Sarosiek, Irene
Related research
Other NIH-funded projects on the same topics.
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New England Gastroparesis Consortium: Neurobiology of Gastroparesis
A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.
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Pediatric and Young Adult Gastroparesis Registry and Disease Course
This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.
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Pediatric gastroparesis: building a nationwide patient registry
This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.
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Gut-resident macrophages and gastric function in gastroparesis
A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.
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Gastric electrical stimulation for stomach pain in gastroparesis
A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.
-
Peptide therapies for gastroparesis in diabetes
A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.