NIH-funded research R21 grant

Parental alcohol and cannabis use before, during, and after pregnancy

Official title: Parental alcohol and cannabis before and during pregnancy: a pilot study

Funded at University of California, San Diego · NIH-11195047 · Data updated 2026-11-12

This project looks at how pregnant people and their partners use alcohol and cannabis before, during, and after pregnancy to learn about timing and patterns of co-use.

More Pregnancy research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 20, 2024
Project endAugust 31, 2026
Funding year2025
Award (this year)$222,800
NIH project number5R21AA031765-02
Project IDNIH-11195047 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are people who are currently pregnant (preferably early in pregnancy) and their biological fathers who can report on alcohol and cannabis use before, during, and after pregnancy.

Less likely to help

People who are not pregnant, not planning pregnancy, or seeking immediate clinical treatment for substance use may not get direct benefit from participating in this observational pilot.

What this research studies

You and the biological father will be asked about alcohol and cannabis use before pregnancy, during each trimester, and after the baby is born so researchers can see how patterns change over time. The pilot will enroll pregnant people and their partners and collect repeated reports about whether substances were used together or separately and whether one substance replaces the other. The team will use these data to map distinct use patterns and gather feasibility information needed for a larger cohort study. Findings will help plan future research that links use patterns to birth and child development outcomes.

Why it matters

Potential benefit: If successful, this work could help doctors give clearer guidance about combined alcohol and cannabis use around pregnancy and support prevention efforts to reduce risks to babies.

How similar studies have gone: Most prior evidence about combined prenatal alcohol and cannabis harm comes from animal studies, so this pilot is relatively novel in collecting paired human parental use data across the perinatal period.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Bandoli, Gretchen E. — University of California, San Diego
  • Study coordinator: Bandoli, Gretchen E.

Related research

Other NIH-funded projects on the same topics.

  • How pregnant women use cannabis and other substances across pregnancy

    This project looks at how women use cannabis before and during pregnancy and how patterns vary by who they are and by local policies, using health records from Kaiser Permanente to understand potential health impacts.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11386446

  • Trajectories of Cannabis Use in Pregnancy

    This study follows pregnant people to understand how cannabis use patterns change across pregnancy and how those patterns relate to birth outcomes and child development.

    NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11383471

  • How cannabis use changes during pregnancy

    This project will follow pregnant people who use cannabis to track how their use changes across pregnancy and identify factors linked to those patterns.

    NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11136878

  • How pregnant people use cannabis (smoking, vaping, edibles) and other substances

    This project looks at the ways pregnant people use different cannabis products and other drugs before and during pregnancy and how those patterns relate to quitting and health outcomes.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11115861

  • Investigating alcohol and cannabis use before and during pregnancy

    This study is looking at how moms and dads use alcohol and cannabis before and during pregnancy to see how it might affect the baby’s development, and it’s for anyone interested in understanding the risks of these substances during this important time.

    NIH research University of California, San Diego · La Jolla, United States · NIH-10951450

  • How women use cannabis before and during pregnancy

    This study looks at how women use cannabis before and during pregnancy, including different ways they consume it like vaping or eating edibles, to see how this varies with their backgrounds and local laws, and how it might affect their health and their baby's health.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-10932969

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.