NIH-funded research NIH-funded research

Pandemic isolation and memory in older Veterans with and without Alzheimer's

Official title: Consequences of social isolation during the COVID-19 pandemic in older adults with and without Alzheimer's disease

Funded at VA Boston Health Care System · NIH-11132620 · Data updated 2026-11-12

This project looks at how COVID-19 social isolation affected thinking and memory in older Veterans with and without Alzheimer's disease.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Boston Health Care System
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 1, 2023
Project endJune 30, 2027
Funding year2026
NIH project number5I01CX002400-03
Project IDNIH-11132620 on NIH RePORTER

Who could benefit from this research

Could help

Older Veterans, including both those diagnosed with Alzheimer's disease and those without dementia, who experienced social isolation during the COVID-19 pandemic are ideal candidates.

Less likely to help

Younger people, non-Veterans, or those without any connection to VA care are unlikely to benefit directly from this specific project.

What this research studies

Researchers will follow older Veterans, some with Alzheimer's disease and some without, to track changes in thinking and memory after pandemic-related social isolation. They will collect information on loneliness and social contact using surveys and use VA medical records and standard cognitive tests to measure memory and daily function. The team will compare Veterans who experienced more isolation to those who had more social support and will examine other pandemic-related factors that might help or worsen outcomes. The goal is to link changes in social connection during COVID-19 to later cognitive and health outcomes.

Why it matters

Potential benefit: If successful, this work could point to social supports or interventions that help protect thinking and memory in older Veterans after periods of isolation.

How similar studies have gone: Prior research links social relationships to better cognition, but studies focused on pandemic isolation in Veterans and people with Alzheimer's are limited.

Where this research is happening

  • VA Boston Health Care System
    Boston, United States
    Active

Researchers

  • Principal investigator: Budson, Andrew — VA Boston Health Care System
  • Study coordinator: Budson, Andrew

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.