Pandemic isolation and memory in older Veterans with and without Alzheimer's
Official title: Consequences of social isolation during the COVID-19 pandemic in older adults with and without Alzheimer's disease
Funded at VA Boston Health Care System · NIH-11132620 · Data updated 2026-11-12
This project looks at how COVID-19 social isolation affected thinking and memory in older Veterans with and without Alzheimer's disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Boston Health Care System NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| NIH project number | 5I01CX002400-03 |
| Project ID | NIH-11132620 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older Veterans, including both those diagnosed with Alzheimer's disease and those without dementia, who experienced social isolation during the COVID-19 pandemic are ideal candidates.
✕Less likely to help
Younger people, non-Veterans, or those without any connection to VA care are unlikely to benefit directly from this specific project.
What this research studies
Researchers will follow older Veterans, some with Alzheimer's disease and some without, to track changes in thinking and memory after pandemic-related social isolation. They will collect information on loneliness and social contact using surveys and use VA medical records and standard cognitive tests to measure memory and daily function. The team will compare Veterans who experienced more isolation to those who had more social support and will examine other pandemic-related factors that might help or worsen outcomes. The goal is to link changes in social connection during COVID-19 to later cognitive and health outcomes.
Why it matters
Potential benefit: If successful, this work could point to social supports or interventions that help protect thinking and memory in older Veterans after periods of isolation.
How similar studies have gone: Prior research links social relationships to better cognition, but studies focused on pandemic isolation in Veterans and people with Alzheimer's are limited.
Where this research is happening
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VA Boston Health Care System
Boston, United States Active
Researchers
- Principal investigator: Budson, Andrew — VA Boston Health Care System
- Study coordinator: Budson, Andrew
Related research
Other NIH-funded projects on the same topics.
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Effects of COVID-19 isolation on older adults with and without Alzheimer's disease
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Using smartphones to spot isolation and loneliness linked to Alzheimer’s risk
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This study looks at how the COVID-19 pandemic changed the care for older adults, especially those with Alzheimer's and related conditions, to help find better ways to support them during tough times.
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How COVID-19 may damage the brain and interact with Alzheimer's risk
This project looks at whether COVID-19 can harm the brain's protective barrier and worsen Alzheimer's-related changes in older adults, and whether effects differ between men and women.
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Investigating how air quality and living conditions affect social isolation and cognitive function in rural communities at risk for Alzheimer's disease.
This study is looking at how air quality and the places we live can affect feelings of loneliness and memory problems in older adults in rural Florida who might be at risk for Alzheimer's disease, and it involves tracking daily activities and social interactions over five years.
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Using telemedicine to improve care for nursing home residents with Alzheimer's and related dementias
This study is looking at how using telemedicine can help nursing home residents with Alzheimer's and related dementias get better care, especially during and after the COVID-19 pandemic, by making it easier for them to see doctors without having to leave their homes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.