Pancreas Knowledge Hub (PanKbase)
PanKbase: a community hub for integrated pancreas knowledge
Creating an online hub that brings together pancreas and islet data so researchers can better understand type 1 diabetes and related conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11289470 on NIH RePORTER |
What this research studies
As someone affected by diabetes, I'm encouraged that this project will gather and link single-cell sequencing and multiplexed imaging data from pancreas and islet studies across the US and Europe. The team will standardize and integrate tissue- and cell-level datasets from existing programs in the Human Islet Research Network so researchers can search and compare results more easily. They will build tools and visualizations based on successful platforms like Pancreatlas and GenomicKB to show cell types, spatial layouts, and biomarkers. Making these combined datasets FAIR and widely available should help researchers spot patterns in how pancreatic cells change in development and in type 1 diabetes.
Who could benefit from this research
Good fit: People with type 1 diabetes, including those with brittle diabetes, or individuals willing to donate pancreatic tissue, islets, or clinical data for research would be most relevant to this effort.
Not a fit: People without diabetes or those who do not contribute samples or clinical data are unlikely to see a direct, immediate benefit from this project.
Why it matters
Potential benefit: If successful, this could speed up discoveries about how type 1 diabetes begins and lead to better diagnostics, prevention strategies, and treatments.
How similar studies have performed: Related resources such as Pancreatlas and GenomicKB have helped researchers access pancreas data, but building a unified, integrated Pancreas Knowledgebase that combines many multimodal datasets is a newer and more ambitious effort.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Parker, Stephen Cj — University of Michigan at Ann Arbor
- Study coordinator: Parker, Stephen Cj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.