Ovarian cancer tissue and data resource
Core B: TCP: Translational Pathology Core
Collects and shares tumor samples and clinical data from people with ovarian cancer to help researchers develop better tests and treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11173700 on NIH RePORTER |
What this research studies
This program collects high-quality, pathology-reviewed samples such as tumor tissue, ascites fluid, blood, pelvic washes, and stool from people seen at the Hillman Cancer Center gynecologic clinics. Samples are collected before treatment and over time during clinical care, processed, de-identified, and linked to clinical information and molecular data. The core centralizes storage, conducts pathology review, and shares specimens and data securely with approved researchers. They also generate patient-derived tumor models to support laboratory studies of new therapies and disease mechanisms.
Who could benefit from this research
Good fit: People diagnosed with ovarian cancer who receive care at the Hillman Cancer Center gynecologic clinics in southwestern Pennsylvania and are willing to consent to donate samples and clinical data.
Not a fit: People without ovarian cancer or those not receiving care at participating clinics cannot contribute samples and are unlikely to gain direct benefit from this resource.
Why it matters
Potential benefit: By supplying well-annotated samples and data, the resource could speed discovery of new biomarkers and treatments for ovarian cancer.
How similar studies have performed: Other cancer biorepositories and translational pathology cores have successfully enabled discoveries of biomarkers and preclinical testing of new therapies, so this is an established, useful approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Modugno, Francesmary — University of Pittsburgh at Pittsburgh
- Study coordinator: Modugno, Francesmary
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.