Outpatient treatment for opioid use disorder and related infections

DAT- Integrated Outpatient Treatment of Opioid Use Disorder and Injection-Related Infections

NIH-funded research University of Kentucky · NIH-10673063

This study is looking at whether people with opioid use disorder and serious infections can safely get their antibiotic treatment at home instead of needing to stay in the hospital, making care easier and more affordable for them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kentucky NIH-funded
Lab location1 site (Lexington, United States)
Project IDNIH-10673063 on NIH RePORTER

What this research studies

This research investigates the effectiveness of outpatient treatment for individuals with opioid use disorder (OUD) who also suffer from severe injection-related infections. It aims to challenge the common assumption that these patients must remain hospitalized to complete their antibiotic treatments. By utilizing outpatient parenteral antibiotic therapy (OPAT), the study seeks to provide a more cost-effective and patient-centered approach to care. The research will explore innovative clinical models that facilitate safe and effective outpatient management of these patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are experiencing severe injection-related infections and are medically stable enough to receive outpatient care.

Not a fit: Patients who are not diagnosed with opioid use disorder or those who are not experiencing injection-related infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options for patients with opioid use disorder and related infections, reducing hospital stays and associated costs.

How similar studies have performed: Previous research has shown that outpatient parenteral antibiotic therapy can be effective for other patient populations, suggesting potential success for this approach in treating patients with opioid use disorder.

Where this research is happening

Lexington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.