Osteosarcoma and leiomyosarcoma patient genomics and data project
Engagement Optimization Unit
This project invites people with osteosarcoma or leiomyosarcoma to share medical records, tumor samples, and health information to build a large database that can help find better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11196740 on NIH RePORTER |
What this research studies
You can join through two patient-facing websites created for the osteosarcoma and leiomyosarcoma communities and give consent online. Participants will be asked to share medical records, answer surveys, and provide tumor or blood samples for genomic and molecular analysis. Researchers will combine the clinical, genomic, and patient-reported data into a shared database and use computational methods to look for new treatment targets and ways to improve care. The project is designed with patient partners to make participation easier and to help speed discoveries that could lead to new trials and standards of care.
Who could benefit from this research
Good fit: People of any age diagnosed with osteosarcoma or leiomyosarcoma who can share medical records, provide samples, and complete surveys are ideal candidates.
Not a fit: People without osteosarcoma or leiomyosarcoma, or those unable or unwilling to share records or samples, are unlikely to gain direct benefit from participating.
Why it matters
Potential benefit: If successful, this could speed discovery of targeted therapies, new clinical trials, and better diagnostic tools that improve outcomes and reduce treatment side effects for people with these rare sarcomas.
How similar studies have performed: Other patient-driven genomics projects have successfully created large shared datasets in different cancers, so this approach is promising though less tested specifically for osteosarcoma and leiomyosarcoma.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Mack, Jennifer W — Broad Institute, INC.
- Study coordinator: Mack, Jennifer W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.