Origins of T cells from embryonic stages
Official title: Embryonic origins of T cells
Funded at Cornell University · NIH-11400540 · Data updated 2026-11-12
A short, friendly overview of a study exploring how early life development shapes adult T cells and their role in immune health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project start | September 1, 2025 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $199,560 |
| NIH project number | 5R21AI193994-02 |
| Project ID | NIH-11400540 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+ years) who may benefit from advances in immunotherapy or immune health research could participate in future related studies or trials.
✕Less likely to help
This grant’s primary focus is basic science; individual patient benefits depend on future translational steps.
What this research studies
This project looks at how T cells, the immune system’s soldiers, may come from different early-life sources than previously thought. By studying embryonic and non-traditional progenitors, researchers aim to map how these early origins influence T cell behavior in adulthood. The work is designed to translate basic science into better understanding of immune-related diseases and cancer. The grant supports a focused, two-year line of inquiry at Cornell University led by Dr. Brian Rudd.
Why it matters
Potential benefit: If successful, findings could lead to new approaches for designing better cancer immunotherapies and treatments for immune diseases.
How similar studies have gone: Previous work shows that early-life progenitors can influence adult T cell populations, suggesting notable potential for advancing therapies.
Where this research is happening
-
Cornell University
Ithaca, United States Active
Researchers
- Principal investigator: Rudd, Brian David — Cornell University
- Study coordinator: Rudd, Brian David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.