NIH-funded research R01 grant

Origins of Basic Reasoning in the Developing Brain

Official title: Origins of Basic Reasoning in the Developing Brain: Interdisciplinary Research

Funded at Carnegie-Mellon University · NIH-11339992 · Data updated 2026-11-12

A study at Carnegie Mellon will look at how young children develop the ability to reason about relationships, using behavioral tests and brain imaging to understand what changes as autism may affect this skill.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCarnegie-Mellon University
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startSeptember 1, 2026
Project endAugust 31, 2031
Funding year2026
Award (this year)$339,574
NIH project number1R01HD121553-01
Project IDNIH-11339992 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are children aged 3–7 with or without autism who can participate in behavioral tasks and noninvasive brain imaging.

Less likely to help

Very young children or those unable to participate in imaging or behavioral tasks may receive limited direct benefit.

What this research studies

This project follows children aged 3 to 7 as researchers combine behavioral tasks with brain imaging to map how relational reasoning develops. It compares human children with non-human primates to identify which parts of this thinking are unique to humans and how brain networks reorganize during early childhood. The team tests a framework that splits relational reasoning into general learning, human-specific memory growth, and cultural support through symbols. By examining neural systems involved in visual processing and other brain pathways, the study aims to reveal how relational thinking emerges and changes over time. The research could shed light on why relational reasoning is affected in autism and related learning differences.

Why it matters

Potential benefit: Improved understanding of how children develop relational thinking, which could inform education and intervention strategies for autism and related conditions.

How similar studies have gone: Similar work in developmental neuroscience has shown links between neural development and cognitive skills, with ongoing research improving comprehension of these processes.

Where this research is happening

  • Carnegie-Mellon University
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Cantlon, Jessica F — Carnegie-Mellon University
  • Study coordinator: Cantlon, Jessica F

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.