NIH-funded research U01 cooperative agreement

Orally delivered tick-control treatment for deer and small rodents to reduce Lyme disease risks

Official title: Suppression of Host-Seeking Ixodes scapularis Abundances and Interruption of Pathogen Transmission Through Orally Delivered Systemic Acaricide Treatment of White-tailed Deer and Peromyscus spp.

Funded at Connecticut Agricultural Experiment Sta · NIH-11509998 · Data updated 2026-11-12

A study will test giving existing acaricides through oral baits to deer and small rodents to lower tick numbers and reduce pathogen transmission.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionConnecticut Agricultural Experiment Sta
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$1,000,000
NIH project number5U01CK000665-05
Project IDNIH-11509998 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are communities and environments with high tick exposure where deer and small mammals play a key role in tick life cycles.

Less likely to help

Public health benefit may be limited in areas without these tick-host dynamics or where deer/mammal hosts are not present.

What this research studies

Researchers will apply commercially available acaricides to host animals (deer and Peromyscus mice) by coating food or using targeted dosing. The approach aims to decrease the number of host-seeking Ixodes scapularis ticks that carry human pathogens, in several locations with different mammal communities. The team will develop standardized procedures so homeowners or vector-control pros could implement this strategy in communities at risk for Lyme disease. This work involves field testing, efficacy assessment, and protocol creation to support practical, real-world use.

Why it matters

Potential benefit: If successful, communities could see fewer Lyme disease-carrying ticks and lower human exposure.

How similar studies have gone: Previous work has shown that host-targeted tick control can reduce tick abundance in some settings, but this study tests a systematic, field-based implementation.

Where this research is happening

  • Connecticut Agricultural Experiment Sta
    New Haven, United States
    Active

Researchers

  • Principal investigator: Williams, Scott C. — Connecticut Agricultural Experiment Sta
  • Study coordinator: Williams, Scott C.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.