Oral inflammation and gut-brain link in dental patients through practice-based research
Official title: Oral Inflammation and Functional Gastrointestinal Disorders: A Practice-Based Reseach Approach
Funded at Midwestern University (Glendale Az) · NIH-11332694 · Data updated 2026-11-12
A practice-based research program to help dentists and students work together to study how oral inflammation relates to chronic gut-related GI symptoms.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Midwestern University (Glendale Az) NIH-funded |
| Lab location | 1 site (Glendale, United States) |
| Project start | September 13, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $665,368 |
| NIH project number | 5U01DE033265-04 |
| Project ID | NIH-11332694 on NIH RePORTER |
Who could benefit from this research
✓Could help
Dental patients with inflammatory oral conditions and related functional GI symptoms who are treated at the MWU College of Dental Medicine or UC collaborations.
✕Less likely to help
Patients not involved in dental clinics or not connected to the practice-based research network may not benefit directly.
What this research studies
This project builds a sustainable clinical research program at two Midwestern University dental schools and a partner at the University of Chicago to train students and faculty in practice-based research. It focuses on creating training materials, mentorship networks, and collaborations so future dentists can contribute to national dental research networks. The effort is designed to embed research training into dental education and improve real-world patient care. By linking clinical experiences with a national network, patients with oral and functional GI issues may benefit from faster translation of findings into practice.
Why it matters
Potential benefit: If successful, patients could see more evidence-based dental care and a stronger link between oral health and digestive symptoms.
How similar studies have gone: Previous practice-based research networks in dentistry have improved research training and collaboration, though specific outcomes for oral inflammation and GI symptoms are still emerging.
Where this research is happening
-
Midwestern University (Glendale Az)
Glendale, United States Active
Researchers
- Principal investigator: Mitchell, John C — Midwestern University (Glendale Az)
- Study coordinator: Mitchell, John C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.