Oral HPV Testing for People Living with HIV Using Home Kits
Persistent oral HPV among diverse PLWH: A pilot study to evaluate the feasibility and acceptability of testing for oral HPV DNA infection with mail-delivered sample collection kits.
['FUNDING_R03'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11168926
This pilot aims to see if it's practical and acceptable for people living with HIV to test for oral HPV infection using sample collection kits sent to their homes.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11168926 on ClinicalTrials.gov |
What this research studies
People living with HIV have a higher chance of developing throat cancer, and most of these cancers are caused by human papillomavirus (HPV). It's challenging to identify those with persistent oral HPV infection who might be at higher risk, especially across different racial and ethnic groups. This project explores a new way to make it easier for people to participate in testing by using mail-delivered kits. We want to understand if this method is both easy to use and acceptable to a diverse group of people living with HIV.
Who could benefit from this research
Good fit: Ideal candidates are people living with HIV from diverse racial and ethnic backgrounds who are interested in testing for oral HPV infection.
Not a fit: Patients who do not have HIV or are not at risk for oral HPV-related throat cancer may not directly benefit from this specific screening method.
Why it matters
Potential benefit: If successful, this approach could make it much simpler to screen for oral HPV among people living with HIV, potentially leading to earlier detection and better outcomes for throat cancer.
How similar studies have performed: While the link between HIV, HPV, and throat cancer is known, there are few studies on racial/ethnic differences in oral HPV persistence or the feasibility of mail-delivered testing in this specific population.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HERNANDEZ, ALEXANDRA LYDIA — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: HERNANDEZ, ALEXANDRA LYDIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, Cancer Induction