NIH-funded research R21 grant

Optimizing spinal stimulation levels to improve walking for children with cerebral palsy

Official title: Optimizing spinal stimulation intensity for gait training in cerebral palsy

Funded at University of Washington · NIH-11310983 · Data updated 2026-11-12

A non-invasive spinal cord stimulation approach is tested with gait training to help children with cerebral palsy walk more easily and with less stiffness.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington
NIH-funded
Lab location1 site (Seattle, United States)
Project startJune 1, 2026
Project endMay 31, 2028
Funding year2026
Award (this year)$383,200
NIH project number1R21HD121135-01
Project IDNIH-11310983 on NIH RePORTER

Who could benefit from this research

Could help

Ambulatory children with bilateral cerebral palsy, around 4–10 years old, who can participate in treadmill and overground walking sessions.

Less likely to help

Children with non-ambulatory CP or other major medical conditions may not benefit from this specific protocol.

What this research studies

This project looks at how different levels of spinal stimulation affect walking in children with cerebral palsy during treadmill and overground training. Researchers will systematically test several stimulation intensities and measure changes in gait patterns, muscle activity, and movement quality. The goal is to find the most effective and comfortable stimulation level that can be used consistently in clinical practice. If successful, this could lead to more reliable protocols for improving mobility in kids with CP.

Why it matters

Potential benefit: If successful, the study could lead to clearer guidelines for spinal stimulation therapies that improve walking for children with CP.

How similar studies have gone: Preliminary studies show promise for spinal stimulation paired with training, but standardized intensity methods are needed; this study advances that standardization.

Where this research is happening

  • University of Washington
    Seattle, United States
    Active

Researchers

  • Principal investigator: Steele, Katherine M — University of Washington
  • Study coordinator: Steele, Katherine M

Related research

Other NIH-funded projects on the same topics.

  • Dynamic Brain Imaging of Cerebral Palsy Gait

    This project uses advanced brain and spinal imaging to understand how cerebral palsy affects the way young people plan and control their leg movements during walking.

    NIH research Father Flanagan's Boys' Home · Boys Town, United States · NIH-11377566

  • Understanding Movement in Cerebral Palsy

    This project aims to better understand how brain and spinal cord changes affect walking and leg movements in young people and adults with cerebral palsy.

    NIH research Father Flanagan's Boys' Home · Boys Town, United States · NIH-11167633

  • Investigating how brain and spinal cord function affects walking in children with cerebral palsy

    This study is looking at how the brain and spinal cord work together to help kids with cerebral palsy walk better, using safe imaging techniques to learn more about their movements and senses, so we can find better ways to support them.

    NIH research Father Flanagan's Boys' Home · Boys Town, United States · NIH-10909942

  • Gait speed from wearable sensors to guide ALS trials

    A patient-friendly look at using wearable sensors to measure how fast people with ALS walk, to help run better ALS trials.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11622545

  • Measuring how kids with cerebral palsy adapt their walking

    A study to understand how children with cerebral palsy learn and adjust walking, and how personalized feedback during walking might improve their mobility.

    NIH research University of Washington · Seattle, United States · NIH-11617681

  • Movement-Enhanced Walking Training to Improve Balance After Stroke

    A specialized treadmill training using a cable-driven device, called Movement Amplification Environment (MAE), helps people with chronic stroke improve walking balance by enhancing their own movement awareness.

    NIH research Edward Hines Jr VA Hospital · Hines, United States · NIH-11597313

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.