Optimizing seizure treatment for children in emergency medical services
Pediatric Dose Optimization for Seizures in EMS (PediDOSE)
This study is looking to make it easier and quicker for paramedics to give the right amount of medicine to kids having seizures, so they can get better care when they need it most.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11177281 on NIH RePORTER |
What this research studies
This research focuses on improving the treatment of seizures in children by emergency medical services (EMS). It aims to address the common issue of under-dosing and delays in administering anti-seizure medication, specifically midazolam. The study will implement a standardized, age-based dosing method to simplify the process for paramedics, making it faster and more effective in treating pediatric seizures. By conducting a large trial across 20 EMS systems, the research seeks to enhance the effectiveness and safety of seizure management in children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who experience seizures and require emergency medical intervention.
Not a fit: Patients who do not experience seizures or are outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and timely treatment of seizures in children, reducing the risk of complications such as brain damage.
How similar studies have performed: Previous research has shown that standardized dosing approaches can improve treatment outcomes in emergency settings, suggesting a promising potential for this method.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Shah, Manish Ishwar — Stanford University
- Study coordinator: Shah, Manish Ishwar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.