Optimizing microbubble doses for delivering drugs to the brain
Microbubble Dose Optimization for Image-Guided Drug Delivery
This study is exploring a new way to help deliver medicine directly to the brain using tiny bubbles and sound waves, which could make treatments for brain cancer and other neurological conditions safer and more effective without needing surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project ID | NIH-10652332 on NIH RePORTER |
What this research studies
This research investigates a noninvasive method to deliver drugs directly to the brain by using microbubbles and focused ultrasound. The approach aims to temporarily open the blood-brain barrier, allowing targeted drug delivery while minimizing the need for invasive surgical procedures. By optimizing the dosage of microbubbles, the study seeks to enhance the effectiveness and safety of this drug delivery method. Patients may benefit from improved treatments for brain cancer and neurological diseases through this innovative technique.
Who could benefit from this research
Good fit: Ideal candidates include individuals with brain cancer or neurological diseases who require targeted drug therapies.
Not a fit: Patients with conditions that do not involve the brain or those who are not candidates for drug delivery via the blood-brain barrier may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective drug delivery methods for treating brain conditions.
How similar studies have performed: Other research has shown promise with similar microbubble-assisted techniques, indicating potential for success in this area.
Where this research is happening
Boulder, UNITED STATES
- University of Colorado — Boulder, United States (Active)
Researchers
- Principal investigator: Borden, Mark Andrew — University of Colorado
- Study coordinator: Borden, Mark Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.