Optimizing HIV care in resource-limited settings using cost-effectiveness analysis
Value of Information and Cost-Effectiveness Analysis to Optimize Research and Policy Decisions for HIV Care in Resource Limited Settings
['FUNDING_CAREER'] · UNIVERSITY OF MINNESOTA · NIH-10876277
This study is looking to find better ways to treat adults in Kenya who are not responding well to their current HIV medication, with the goal of improving their health and treatment options.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10876277 on ClinicalTrials.gov |
What this research studies
This research focuses on improving HIV treatment strategies for adults in Kenya who are experiencing treatment failure on dolutegravir-based antiretroviral therapy (ART). By employing innovative value of information analysis methods, the project aims to prioritize and design clinical studies that can enhance treatment guidelines for managing virologic failure. The research will utilize a stochastic model to evaluate the cost-effectiveness of drug resistance testing and identify the most beneficial research studies for patients. Ultimately, this work seeks to maximize health benefits in resource-limited settings where funding for research is constrained.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 15 years and older living with HIV in resource-limited settings, particularly those on dolutegravir-based ART who are facing virologic failure.
Not a fit: Patients who are not living with HIV or those who are not experiencing treatment failure on dolutegravir-based ART may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective HIV treatment strategies, improving health outcomes for patients experiencing treatment failure.
How similar studies have performed: Previous research has shown success in using cost-effectiveness analysis to inform treatment strategies in HIV care, indicating that this approach has potential for meaningful impact.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DUARTE, HORACIO ADRIAN — UNIVERSITY OF MINNESOTA
- Study coordinator: DUARTE, HORACIO ADRIAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus