Optimizing brain stimulation parameters for epilepsy treatment
Patient Specific Parameter Optimization of Thalamic Stimulation for Treatment of Epilepsy
This study is looking to make deep brain stimulation (DBS) for epilepsy even better by using smart technology to personalize the settings for each patient, helping to control seizures more effectively.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10928156 on NIH RePORTER |
What this research studies
This research focuses on improving deep brain stimulation (DBS) for epilepsy by optimizing the parameters used in the stimulation process. It aims to develop a systematic approach that utilizes machine learning algorithms to fine-tune stimulation settings, which could lead to better seizure control for patients. The study will involve collecting data from patients using Medtronic’s DBS Percept system, allowing for real-time adjustments based on individual responses. By analyzing these responses, the research seeks to enhance the effectiveness of DBS in reducing seizure frequency and potentially achieving seizure freedom.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with epilepsy who have not achieved satisfactory seizure control with existing treatments.
Not a fit: Patients who have not been diagnosed with epilepsy or those who have contraindications for deep brain stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve seizure control for epilepsy patients, leading to a better quality of life.
How similar studies have performed: Previous research has shown promise in optimizing deep brain stimulation settings using machine learning techniques, indicating potential for success in this novel approach.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Mcgovern, Robert a — University of Minnesota
- Study coordinator: Mcgovern, Robert a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.