Optimizing a therapy for liver cancer treatment
Official title: Delivery optimization of a transarterial ablative therapy
Funded at University of Tx Md Anderson Can Ctr · NIH-11165245 · Data updated 2026-11-12
This study is working on making a liver cancer treatment called thermoembolization better by using math to understand how it works in the body, so that it can be delivered more safely and effectively to help people with liver cancer feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | March 15, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $536,836 |
| NIH project number | 1R01CA301555-01 |
| Project ID | NIH-11165245 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with hepatocellular carcinoma who may benefit from advanced therapeutic approaches.
✕Less likely to help
Patients with liver cancer who are not eligible for thermoembolization or have other contraindications may not benefit from this research.
What this research studies
This research focuses on improving a specific treatment method for liver cancer called thermoembolization. It involves developing mathematical models to understand how different chemical reactions and fluid flows occur in biological tissues during the treatment. By validating these models in animal studies, the researchers aim to optimize how the therapy is delivered to patients, ensuring it is both effective and safe. The ultimate goal is to enhance treatment outcomes for individuals with hepatocellular carcinoma.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with liver cancer.
How similar studies have gone: Previous research has shown promise in optimizing treatment delivery methods for cancer therapies, suggesting that this approach could yield significant advancements.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Fuentes, David — University of Tx Md Anderson Can Ctr
- Study coordinator: Fuentes, David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.