Optimizing a smoking cessation program for people living with HIV

Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

NIH-funded research New York University · NIH-10898674

This study is looking for ways to help people with HIV quit smoking by trying out different support methods, like motivational talks, peer support, text reminders, and nicotine aids, to find the best combination that makes quitting easier and more effective for them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10898674 on NIH RePORTER

What this research studies

This research aims to improve smoking cessation efforts specifically for individuals living with HIV by addressing both patient and clinical barriers to quitting. It employs a Multiphase Optimization Strategy (MOST) to test various intervention components, including motivational interviewing, peer mentoring, text messaging, and nicotine replacement therapies. By determining the most effective combination of these components, the study seeks to create a cost-effective and sustainable smoking cessation package tailored for HIV clinical care. Patients participating in this research will have access to innovative support methods designed to enhance their chances of quitting smoking successfully.

Who could benefit from this research

Good fit: Ideal candidates for this research are smokers who are living with HIV and seeking assistance to quit smoking.

Not a fit: Patients who do not smoke or are not living with HIV may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve smoking cessation rates among individuals living with HIV, leading to better overall health outcomes.

How similar studies have performed: Previous research has shown promise in using similar intervention components for smoking cessation, but this specific optimization approach is novel.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.