Optimized low-cost EVO weight-loss program
Evaluating the EVO treatment optimized for resource constraints: Elements Vital to treat Obesity
This project will create a simpler, lower-cost version of a proven weight-loss program to help adults with obesity lose weight.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tennessee Knoxville NIH-funded |
| Lab location | 1 site (Knoxville, United States) |
| Project ID | NIH-10878889 on NIH RePORTER |
What this research studies
This project aims to build a simpler, lower-cost version of the Diabetes Prevention Program by figuring out which parts are truly needed. Researchers will test combinations of program elements—like coach calls, text messages, meal replacements, self-monitoring, and app-based tools—to find the smallest set that still produces weight loss. You would be asked to use the program (mostly through an Android app and some coaching), report your weight and behaviors, and possibly attend occasional in-person visits. The team uses efficient randomized experiments to compare options so they can assemble an affordable package that reduces burden and cost while keeping benefits.
Who could benefit from this research
Good fit: Adults with overweight or obesity who want to lose weight and are willing to use an app and brief coaching would be ideal candidates.
Not a fit: People who need surgical weight-loss care, have unstable medical conditions, are pregnant, or cannot use smartphone-based tools may not benefit from this approach.
Why it matters
Potential benefit: If successful, this could give patients an affordable, easier-to-use weight-loss program that achieves meaningful weight loss.
How similar studies have performed: The Diabetes Prevention Program has produced about 6.5 kg weight loss and earlier trials like Opt-IN showed promising results with streamlined approaches, so this work builds on proven methods.
Where this research is happening
Knoxville, United States
- University of Tennessee Knoxville — Knoxville, United States (Active)
Researchers
- Principal investigator: Pfammatter, Angela Fidler — University of Tennessee Knoxville
- Study coordinator: Pfammatter, Angela Fidler
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.