Optimal Dosing for Pregnant Women: Guiding Better Medicines for Mom and Baby

Who could benefit from this research

What this research studies

This project will enroll pregnant women taking drugs as part of their standard care and collect biological samples throughout pregnancy and after birth, including cord blood and infant blood, to understand how pregnancy changes drug exposure. The team will build a biorepository from these samples to support future precision-dosing research. Advanced pharmacokinetic and pharmacodynamic modeling will be used to determine optimal dosing for these drugs during pregnancy. The study seeks to address a critical gap where current dosing information for pregnant women is often lacking. The overall goal is to improve maternal and fetal outcomes by informing better dosing guidelines.

Why it matters

Where this research is happening

• George Washington University
  Washington, United States Active

Researchers

• Principal investigator: Clifton, Rebecca Gersnoviez — George Washington University
• Study coordinator: Clifton, Rebecca Gersnoviez

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.